Pathway-Centric Tools and Technology™
Newsletter July  2004
  • Oligo GEArray Focused DNA Microarray
  • Are you getting all of your messages? Say Hello to Ampo!
  • The Internal Normalizer: Making Conventional RT-PCR More Quantitative
  • Use of Enzymatically Generated and Chemically Synthesized siRNA
  • The SABiosciences 2004/2005 Product Catalog is here: Order yours now!

Oligo GEArray Focused DNA Microarray:
A robust, flexible, and cost effective tool for gene expression profiling

Oligo GEArray is a new oligonucleotide-based gene expression array platform. It combines cutting-edge oligonucleotide design with the high-binding capacity of a nylon membrane based array. The Oligo GEArray also takes full advantage of up-to-date pathway and gene function information.


Are you getting all of your messages? Say Hello to Ampo!

The AmpoLabeling-LPR method enzymatically converts experimental RNA into labeled cDNA probe for hybridization with our pathway-specific cDNA GEArrays. This method improves gene expression profiling sensitivity and reliability over conventional methods, and provides results more similar to those of RT-PCR.


The Internal Normalizer: Making Conventional RT-PCR More Quantitative

The accuracy of conventional RT-PCR for relative gene expression profiling is limited by variability in the quantity or quality of the original RNA samples. Internal Normalizer technology makes it feasible to use a housekeeping gene as a universal reference in the same tube as the PCR for the gene of interest and to correct for systematic errors.


Use of Enzymatically Generated and Chemically Synthesized siRNA

Small interfering RNA can be either synthesized chemically or enzymatically generated. In this article, we discuss the advantages and disadvantages of using these two methods to successfully and specifically knock down the expression of your gene of interest.


The 2004/2005 Catalogs are hot off the presses!

The 2004/2005 catalog is now available, and we would be happy to mail you a copy. Please send an e-mail to customercare@sabiosciences.com and include the word "catalog" in the subject line. We'll need your name, e-mail address, and complete mailing address (including institution, postal code and country).

SABiosciences Corp.
7320 Executive Way, Suite 101
Frederick, MD 21704
Phone:  (888) 503-3187 / (301) 682-9200 
E-mail:  support@sabiosciences.com (Technical Support)