Oligo GEArray® Rat Cancer PathwayFinder™ Microarray

HybTube Format Cat. No.: ORN-033
HybPlate Format Cat. No.: ERN-033 		 
Description
The Oligo GEArray® Rat Cancer PathwayFinder™ Microarray profiles the expression of 113 genes representative of the six biological pathways involved in transformation and tumorigenesis listed below. Through a simple side-by-side hybridization experiment you can simultaneously determine which of the 6 pathways is involved in your experimental treatment. Once you have identified the pathways involved in your treatment with this microarray, you can then perform focused profiling experiments using our pathway-specific GEArray Microarrays. Through a simple side-by-side hybridization experiment you can determine differential gene expression between your samples.

Need more information about GEArray products? please visit Microarray Home or send Email to Technical Support
Useful Links
Pricing and Ordering Gene Table GEArray Service
User Manual White Paper GEArray ThermoShaker
Related Products for the Genes on This Array
shRNA Plasmids qPCR Gene Assays Modify This Array
Functional Gene Grouping

Cell Cycle Control and DNA Damage Repair: Atm, Brca1, Brca2, Ccnd1, Ccne1, Cdc25a, Cdk2, Cdk4, Cdkn1a (p21Waf1), Cdknn1b (p27Kip1), Cdkn2a (p16Ink4), Chek2 (Rad53), E2f1, Mdm2, Prkdc, Pten, Rb1, Tp53.

Apoptosis and Cell Senescence: Apaf1, Bad, Bak1, Bax, Bcl2, Bcl2l1 (bcl-X), Birc5 (survivin), Casp8, Casp9, Cflar, Gzma, Htatip2, Tert (telomerase), Tnfrsf1a, Tnfrsf6 (Fas), Tnfrsf10b (DR5).

Signal Transduction Molecules and Transcription Factors: Akt1, Akt2, Ctnnb1 (Catnb), Erbb2, Ets2, Fos, Grb2, Jun, Map2k1 (MEK), Mapk14 (p38 MAPK), Myc, Nfkb1, Nfkbia (IkBa), Pik3c2a, Pik3cb, Pik3r1, Raf1, Rasa1, Sncg, Src.

Adhesion: Cd44, Cdh1, Icam1, Itga1, Itga2, Itga3, Itga4, Itga5, Itga6, Itgav, Itgb1, Itgb3, Itgb5, LCO368070 (Pnn), Mcam, Mtss1, Ncam1.

Angiogenesis: Agpt2 (angiopoietin-2), Angpt1, Bai1, Col18a1 (endostatin), Egf, Egfr, Fgf1, Fgf2, Fgfr2, Flt1, Hgf, Ifna1, Ifnb1, Igf1, Pdgfa, Pdgfb, Tek, Tgfb1, Tgfbr1 (ALK-5), Thbs2, Tnf, Vegfa.

Invasion and Metastasis: Kai1, Kiss1, Met, Mmp1a (collagenase-1), Mmp2, Mmp9, Mta1, Mta2, Nme1, Plau (uPA), Plaur (uPAR), S100a4, Serpinb2, Serpinb5 (maspin), Serpine1 (PAI1), Spp1 (osteopntin), Syk, Timp1, Timp3, Twist1.
Storage Conditions
Please check the kit components immediately after you receive this package. SABiosciences is only responsible for missing items reported within two (2) business days of receipt.

GEArray microarrays are shipped at ambient temperature enclosed in either a HybTube or ExpressPak Storage Box. They should be stored at -20 ºC upon receipt.

References
  1. Hanahan, D. and Weinberg, R.A. (2000) The Hallmarks Of Cancer. Cell 100: 57-70.
  2. Tsatsanis, C. and Spandidos, D.A. (2000) The Role Of Oncogenic Kinases In Human Cancer. Int J Mol Med 5: 583-590.
  3. Meyer, T. and Hart, I.R. (1998) Mechanisms Of Tumour Metastasis. Eur J Cancer 34: 214-221.
  4. Detmar, M. (2000) Tumor Angiogenesis. JID Symposium Proceedings 5: 20-23.
  5. Klingelhutz, A.J. (1999) The Roles Of Telomeres And Telomerase In Cellular Immortalization And The Development Of Cancer. Anticancer Res 19: 4823-4830.
  6. Kaufmann, S.H. and Gores, G.J. (2000) Apoptosis In Cancer: Cause And Cure. BioEssays 22: 1007-1017.
  7. Lowe, S.W. and Lin, A.W. (2000) Apoptosis In Cancer. Carcinogenesis 21: 485-495.
  8. Funk, J.O. (1999) Cancer Cell Cycle Control. Anticancer Res 19: 4772-4780.
  9. Molinari, M. (2000) Cell Cycle Checkpoints And Their Inactivation In Human Cancer. Cell Prolif 33: 261-274.
  10. Clezardin, P. (1998) Recent Insights Into The Role Of Integrins In Cancer Metastasis. Cell Mol Life Sci 54: 541-548.
Usefullink
Microarray Home
Cataloged Microarrays
Pricing and Ordering
User Manual
Gene Table
White Paper
  PCR Primers  
  Citations  
Product Support
How It Works
Download Brochure
  Technical Resources  
  Slide Presentation  
  Register for Web Seminar  
Copyright © 2008 SABiosciences Corporation