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Apoptosis genes:

Abl1, Atm, Brca1, Mbd4, Mgmt, Mlh1, Prkdc, Rad21, Tp53.

Cell cycle genes:

Cell cycle arrest: Chek1, Ddit3, Gadd45a, Gtse1, Hus1, Msh2, Sesn1.
Cell cycle checkpoint: Brca2, Pinx1, Rad1, Rad9, Smc1l1.
Other cell cycle genes: Atm, Atr, Chaf1b, Cspg6, Rad17, Rad21, Rbbp4, Terf1, Terf2, Tlk1, Tlk2.

DNA repair genes:

Damaged DNA binding: Brca1, Ddb1, Ercc1, Msh2, Msh5, Msh6, Pnkp, Rad1, Trpc2, Xpa, Xpc, Xrcc1, Xrcc3.
Base-excision repair: Adprt, Mare, Mbd4, Mpg, Mutyh, Nthl1, Ogg1, Trad.
Nucleotide-excision repair: Dclre1a, Ercc2, Ercc3, Ercc5, Fancc, Nthl1, Poll, Rad23a, Rad23b, Slk, Xpa, Xpc.
Double-strand break repair: Brca2, Cib1, G22p1, Mre11a, Prkdc, Rad52, Xrcc4, Xrcc5.
Mismatch repair: Mlh1, Mlh3, Msh2, Msh5, Msh6, Pms2, Pold3, Trex1, Trex2.
Others: Apex1, Apex2, Atm, Atrx, Chaf1b, Cry2, Cspg6, Ercc4, Ercc6, Exo1, Fancl, Fen1, Gtf2h1, Gtf2h2, Gtf2h4, Lig1, Lig3, Lig4, Mgmt, Mif, Neil1, Pcna, Pold1, Pole, Poli, Polk, Polq, Pttg1, Rad17, Rad18, Rad21, Rad50, Rad54b, Rad54l, Rad9, Rad9b, Rbbp4, Rbm14, Rev1l, Rev3l, Smc1l1, Srd5a1, Sumo1, Tdg, Tnp1, Ube2a, Ube2b, Ube2n, Uble1a, Ung, Wrn, Wrnip1, Xab2, Xdh, Xrn2.

GEArray microarrays are shipped at ambient temperature enclosed in either a HybTube or ExpressPak Storage Box. They should be stored at -20 ºC upon receipt.

1. Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ Jr, DiStefano PS, Chiang LW, Greenberg ME. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 2002 Apr 19; 296 (5567): 530-4
2. Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 2001 Apr 24; 98 (9): 5116-21
3. Li Z, Li JJ. Effector genes altered in mcf-7 human breast cancer cells after exposure to fractionated ionizing radiation. Radiat Res. 2001 Apr; 155 (4): 543-53.
4. RoblesAI, Bemmels NA, Foraker AB, Harris CC. APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis. Cancer Res 2001 Sep 15; 61 (18): 6660-4
5. Kannan K, Amariglio N, Rechavi G, Jakob-Hirsch J, Kela I, Kaminski N, Getz G, Domany E, Givol D. DNA microarrays identification of primary and secondary target genes regulated by p53. Oncogene 2001 Apr 26; 20 (18): 2225-34
6. Zhou BB, Elledge SJ. The DNA damage response: putting checkpoints in perspective. Nature 2000 Nov 23; 408 (6811): 433-9
7. Bartek J, Lukas J. Mammalian G1- and S-phase checkpoints in response to DNA damage. Curr Opin Cell Biol 2001 Dec; 13 (6): 738-47
8. Carr AM. Cell cycle. Piecing together the p53 puzzle. Science 2000 Mar 10; 287 (5459): 1765-6
9. MacLachlan TK, Somasundaram K, Sgagias M, Shifman Y, Muschel RJ, Cowan KH, El-Deiry WS. BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression. J Biol Chem 2000 Jan 28; 275 (4): 2777-85
10. Yu J, Zhang L, Hwang PM, Rago C, Kinzler KW, Vogelstein B. Identification and classification of p53-regulated genes. Proc Natl Acad Sci U S A 1999 Dec 7; 96 (25): 14517-22