Need more information about GEArray products? please visit Microarray Home or send Email to Technical Support

Cytokines:
Chemokines: CCL1, CCL11, CCL13, CCL17, CCL18, CCL19, CCL2, CCL20, CCL22, CCL24, CCL3, CCL4, CCL5, CCL7, CCL8, CX3CL1, CXCL1, CXCL2, CXCL3, IL13, IL18, IL8, XCL1.
Interferons: CSF3, IFNA1, IFNB1, IFNG, IL15.
Interleukins: CSF3, IL10, IL11, IL12A, IL12B, IL13, IL13RA1, IL18, IL1A, IL1B, IL2, IL21, IL3, IL4, IL5, IL5RA, IL6, IL7, IL8, IL9.
Tumor Necrosis Factor Family: CD40LG, FASLG, LTA, TNF, TNFSF13, TNFSF7, TNFSF8.
Other Cytokines: CSF1, CSF2, IFNGR1, IL16, IL17, IL19, KITLG, PTPRC, TGFB1, TXLNA.

Cytokine Receptors:
Chemokine Receptors: CCL13, CCR10, CCR2, CCR3, CCR4, CCR5, CCR6, CCR7, CCR8, CX3CR1, XCR1.
Interferon Receptors: IFNAR2, IFNGR1, IFNGR2, IL12B, IL13RA1, IL2RG, IL4R, IL5RA, IL6R, IL9R.
Interleukin Receptors: IL12RB1, IL12RB2, IL13RA2, IL18R1, IL2RA, IL2RG, IL4R, IL5RA, IL6R, IL6ST, IL8RA, IL8RB, IL9R.

Immune Response:
IgE Binding: FCER1A, FCER1G, FCER2, LGALS3, MS4A2.
Isotype Switching: CD40LG, IL10, IL4, TGFB1, TNFSF13.
B cell Activation: CD40, CD40LG, IFNB1, IL10, IL11, IL4, IL7, PTPRC, TNFRSF7.
T cell Activation: CD28, CD86, IL10, IL12B, IL18, IL2, IL21, IL4, IL7, ICOSLG, IRF4, LCK, PTPRC, SFTPD, SYK, TNFRSF7, TRAT1.
T-helper 1 Type Immune Response: IL12B, IL18.
T-helper 2 Type Immune Response: IL10, IL18, IL4.
Cytokine Biosynthesis: CD28, CD86, IL10, IL12B, IL18, IL21, IL4, IL6, IL9, IRF4, SFTPD, TNFRSF7.
Humoral Immune Response: CCL18, CCL2, CCL20, CCL22, CCL3, CCL7, CCR2, CCR6, CCR7, CD28, CD40, IL12A, IL12B, IL12RB1, IL13, IL1B, IL2, IL6, IL7, LTB4R2, MS4A2, SFTPD, XCL1, XCR1, YY1.
Cellular Defense Response: CCL11, CCL5, CCR2, CCR3, CCR5, CCR6, CSF2, CSF3, CX3CR1, IL4, IL8RB.
Other Immune Response Genes: CCL1, CCL13, CCL17, CCL19, CCL24, CCL4, CCL8, CCR4, CSF1, CX3CL1, CXCL1, CXCL2, CXCL3, FASLG, FOS, IFNG, IL15, IL16, IL17, IL18R1, IL19, IL1A, IL2RA, IL2RG, IL3, IL4R, IL5, IL6R, IL6ST, IL8, IL8RA, LTA, LTB4R, LTBR, TNF, TNFSF7, TNFSF8.

Response to Stimulus:
Response to Biotic Stimuli: CCL18, CCL20, CYSLTR1, GATA3, IFNA1, IFNB1.
Response to Chemical Stimuli: CCL1, CCL11, CCL13, CCL17, CCL18, CCL19, CCL2, CCL20, CCL22, CCL24, CCL3, CCL4, CCL5, CCL7, CCL8, CCR2, CCR3, CCR4, CCR5, CCR6, CCR7, CCR8, CX3CR1, CXCL1, CXCL2, CXCL3, FGF2, IL16, IL1A, IL4, IL8, IL8RA, IL8RB, LTB4R2, SFTPD, XCL1, XCR1.
Response to Virus: CCL11, CCL19, CCL22, CCL4, CCL5, CCL8, IFNA1, IFNAR2, IFNB1, IFNG, IFNGR1, IFNGR2, TNF.
Sensory Perception: CCL1, CCL11, CCL13, CCL17, CCL18, CCL19, CCL2, CCL20, CCL22, CCL24, CCL3, CCL4, CCL5, CCL7, CCL8, CXCL2, CXCL3, GATA3, IL16, IL8, IL8RA, IL8RB, XCL1.
Other Genes Involved in the Response to Stimuli: LCK, PDGFB, TXLNA.

Th2 Cytokine Signaling Pathway:
FOS, GATA3, JAK1, JAK3, STAT6, TBX21, TGFB1, YY1.

Apoptosis:
Anti-apoptosis: CCL2, CD40LG, IL10, IL1A, IL2, IL3, TGFB1, TNF, TNFRSF7.
Induction of Apoptosis: FASLG, IFNB1, IL18, LCK, LTA, TNFRSF7, TNFSF8.
Other Apoptosis: CD28, CD40, IL17, IL19, IL1B, IL2RA, IL4, IL6, IL7, LTBR.

Transcription Factors and Their Regulators:
CD86, FOS, GATA3, IL4, IRF4, STAT6, TBX21, TGFB1, TNF, YY1.

GEArray microarrays are shipped at ambient temperature enclosed in either a HybTube or ExpressPak Storage Box. They should be stored at -20 ºC upon receipt.

1. Olivenstein, R., et al. (1999) IL-4 and IL-5 mRNA expression in induced sputum of asthmatic subjects: comparison with bronchial wash. J. Allergy Clin. Immunol. 103(2 Pt 1), 238-45.
2. Rosenwasser, L.J. and L. Borish. (1997) Genetics of atopy and asthma: the rationale behind promoter-based candidate gene studies (IL-4 and IL-10). Am. J. Respir. Crit. Care Med. 156(4 Pt 2), S152-5.
3. Wong, C.K., et al. (2001) Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-gamma, IL-4, IL-10 and IL-13) in patients with allergic asthma. Clin Exp Immunol. 125(2), 177-83.
4. Hellman, C., et al. (2002) Down-regulated IL-5 receptor expression on peripheral blood eosinophils from budesonide-treated children with asthma. Allergy 57(4), 323-8.
5. Medoff, B.D., et al. (2002) IFN-gamma-inducible protein 10 (CXCL10) contributes to airway hyperreactivity and airway inflammation in a mouse model of asthma. J Immunol. 168(10), 5278-86.
6. Romagnani, S. (2002) Cytokines and chemoattractants in allergic inflammation. Mol Immunol. 38(12-13), 881-5.
7. Teran, L.M., et al. (1999) Th1- and Th2-type cytokines regulate the expression and production of eotaxin and RANTES by human lung fibroblasts. Am. J. Respir. Cell. Mol. Biol. 20(4), 777-86.
8. Zou, J., et al. (2002) Microarray profile of differentially expressed genes in a monkey model of allergic asthma. Genome Biol, 3(5), 20.
9. Owen, C. (2001) Chemokine receptors in airway disease: which receptors to target? Pulm. Pharmacol. Ther. 14(3), 193-202.
10. Ochi, H., et al. (1999) T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro. J Exp Med. 190(2), 267-80.
11. Panina-Bordignon, P., et al. (2001) The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics. J Clin Invest 107(11), 1357-64.
12. Ray, A. and L. Cohn. (1999) Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation. J Clin Invest. 104(8), 985-93.
13. Spinozzi, F., et al. (1998) Defective expression of Fas messenger RNA and Fas receptor on pulmonary T cells from patients with asthma. Ann Intern Med. 128(5), 363-9.